opinion on genotoxicity testing strategies applicable to food and 3 feed safety assessment
نویسندگان
چکیده
At the request of the European Food Safety Authority, the Scientific Committee has reviewed the 8 current state-of-the-science on genotoxicity testing strategies and provided a commentary and 9 recommendations on testing strategies, bearing in mind the needs of EFSA’s various Scientific Panels 10 to have appropriate data for risk assessment. It is hoped that this opinion will contribute to greater 11 harmonisation between EFSA Panels on approaches to such testing. 12 13 The purpose of genotoxicity testing for risk assessment of substances in food and feed is: 14
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Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment
The Scientific Committee reviewed the current state-of-the-science on genotoxicity testing and provided a commentary and recommendations on genotoxicity testing strategies. A step-wise approach is recommended for the generation and evaluation of data on genotoxic potential, beginning with a basic battery of in vitro tests, comprising a bacterial reverse mutation assay and an in vitro micronucle...
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